The origin of the corona virus is linked to the insertion of an amino acid cleaving enzyme that binds to a spike protein on a cell.
In the late hours of January 31, 2020, virologist Kristian Andersen emailed Anthony Fauci and told him it was highly unlikely that the genetic sequence responsible for the enzyme bonding to the spike protein was the product of natural selection. In other words, it was manipulated. Fauci emailed bioweapons expert Robert Kadlec four hours later indicating intense worry that the Wuhan lab may have created this cleavage and that he would be implicated. At that time, Kadlec had been serving as Assistant Secretary of HHS for Preparedness and Response in the Trump Administration for two and a half years.
Source: The Real Anthony Fauci by RFK Jr. p. 380.