"A 9-year-old article in the Journal of Evaluation in Clinical Practice shows that the concept of evidence-based medicine, which was launched in the 1990s and has become a byword for high-quality healthcare, has been hijacked and distorted by pharmaceutical companies.

The simplest explanation for this is that evidence-based studies are usually funded by pharmaceutical companies; at the time of writing, the industry paid for 67-75% of all studies.../...

Pharmaceutical companies are multinational corporations that want to generate profits for their shareholders, and in order to make their new proprietary drug look better, they systematically use various more or less sophisticated and deceptive methods." (This summary is written by a group of Swedish doctors that I follow on Telegram, "Läkaruppropet".)
https://onlinelibrary.wiley.com/doi/epdf/10.1111/jep.12147